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In this publication, the results of Assisted Reproduction
performed in 13 countries of Latin America, in 1997, in 78
affiliated centres of the RED were reported. There were 11.530
therapeutic cycles started and 9.900 transferences that include,
among others, 3.906 IVF, 177 GIFT, 3.789 ICSI, 560 OD and
599 cycles with thawed embryos. From these procedures, the
majority was performed in Brazil (45%) and Argentine (21.2%).
39.5% of the transferred cycles are related to IVF procedures
and 38.3% to ICSI. 49 of the 78 centres performed ICSI procedures.
The clinical pregnancy rate (TEC) by aspiration and births
with liveborn were 23.1% and 17.9% for IVF, 28.1% and 23.3%
for ICSI. From the 9.900 transferences performed, 3.105 live
children were born (1.488 unique, 1.072 twins, 473 triplets
and 72 quadruplets or more). This reflects the multiple gestation
rates that were 29.3% for IVF and 27.7% for ICSI. On the other
hand, the TEC by cryopreserved embryos transferred (559 transferences)
was 19.1%, originating 69 births with at least one liveborn.
From the 526 transferences with embryos pertaining to OD cycles,
the TEC by transference was 36.7%, originating 157 births
with at least one liveborn.
For the ovarian stimulation, the combination GnRh + gonadotrophins
was used in 80.9% of the cases, being TEC significantly higher
than in the cycles in which only clomifene or gonadotrophins
were used (24.6% versus 17.3% and 19.6%, respectively).
The TEC decreases when the age of the patient increases in
all procedures. To the interior of each category of age, the
TEC does not differ according to the diagnostic category.
The implantation rates are significantly higher in women aged
under 35 in relation to those aged 35 – 39 when to transfer
1 to 4 embryos. Comparing women aged 35 – 39 with women
aged = 40, the differences are significant only to transfer
5 embryos.
The chance of gestation in IVF increases significantly until
the transference of 3 embryos, and there is not difference
to transfer 4, however, the same does not occur in ICSI, where
the transference of 4 embryos increases significantly the
chance of gestation in relation to 3 embryos. The stabilization
occurs to transfer 5. On the other hand, as in IVF as in ICSI,
in women aged < 35, the multiple gestation rate (MG) is
significantly superior to transfer 3 embryos in relation to
2. The extreme multiple gestation rate (MG) does no differ
significantly in women aged < 35 in relation to women aged
35 – 39, independently to the number of embryos transferred.
The number of stillbirth (10.4%) and perinatal death (10.4%)
increase significantly in the gestations of quadruplets in
relation to triplets and twins.
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