Introduction. The present report corresponds to the twenty-fourth version of the Latin American Registry of Assisted Reproductive Technologies (RLA). This registry summarises the cycles performed by 155 clinics located in fourteen countries, and is the third version of a case-by-case registry.
Methods. All centres uploaded electronically their data, corresponding the procedures performed in 2012; after checking for internal consistency these data were included in RLA´s main database. A total of 47,326 ART procedures were included: 31,857 homologous IVF/ICSI cycles; 10,073 FET (both autologous and heterologous); 5,396 OD cycles; and 1,764 fertility preservation cycles.
Results. Thirty nine per cent of IVF/ICSI cycles were initiated in women 35-39 years, and 31% in women ≥40 years. Delivery rate per oocyte pick up in IVF and ICSI cycles reached 20.9% y 26.5%, respectively. The proportion of multiple delivery was 30.2% (27.8% doubles y 2.4% triplets-and-higher). When >2 embryos were transferred, neither the delivery rate nor the proportion of double delivery increased significantly. However, the proportion of triplets-and-higher did. In OD cycles, the proportion of double delivery and triplets-and-higher was 27.8% y 2.4%, respectively. In FET cycles, the proportion of double delivery and triplets-and-higher was 19.6% y 1.3%, respectively. Multiple delivery was associated with an increase in preterm delivery and perinatal mortality. In IVF/ICSI cycles the proportion of eSET and eDET reached 1.4% and 21.0%, respectively. Delivery rate per embryo transfer when eSET was performed reached 24.5%, and when eDET was performed reached 38.8%. In women aged ≤34 years, the delivery rate per embryo transfer reached 30.0% with eSET, and 42.0% with eDET. In the case of OD, the delivery rate per embryo transfer reached 29.5% with eSET and 40.4% with eDET.
Conclusions: Overall, the delivery rate is similar to that published by different European countries. However, the proportion of double and triplet-and-higher deliveries remain high. In order to diminish the perinatal complications derived thereof, the elective transfer of one or two embryos should be encouraged.