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This report presents information of assisted reproductive technologies performed during 2008 and all babies born up until September 2009. A total of 140 centers, located in eleven countries, contributed with their data. As in previous years, the majority of them are located in Brazil and Argentina.
Preference for Intracytoplasmatic sperm injection (ICSI) persists, reaching 85.4% with respect to in vitro fertilization (IVF) which represented only 14.1% of all cycles. The age of women undergoing ART continues to rise. Of all IVF/ICSI embryo transfers, 43.3% were performed in women aged = 34; 38.7% in women aged 35 to 39; and 18.0% in women aged = 40.
A total of 35,496 ART procedures with an outcome of 10,668 clinical pregnancies and 8,068 deliveries with live-birth were reported. Included in these ART procedures are: 25,898 IVF/ICSI cycles with 7,280 live born; 4,225 frozen/thawed transfer cycles with 814 live born; 4,316 oocyte donation cycles with fresh embryo transfers resulting in 2,206 live born and 942 oocyte donation cycles with frozen/thawed embryo transfers resulting in 249 live born.
In 2008, 176 elective single embryo transfer (eSET) and 2,945 elective dual embryo transfer (eDET) were reported. Both were more frequent in women aged = 35. The clinical pregnancy rate per embryo transfer reached 29% with eSET and 47% with eDET. On the other hand, the clinical pregnancy rate, when two embryos (non-elective) and = 3 embryos were transferred, reached 36.5% and 39.1%, respectively. When eDET was performed, the twin pregnancy rate reached 26%, and = triple pregnancy rate reached 0.3%, compared to 21% and 5% when = 3 embryos were transferred.
Of the 8,350 deliveries registered, 74% were singletons, 23% were twins and 3% were triplets or greater. Consequently, of the 10,875 babies born, 57% were singletons, 35% were twins, and 8% were triplets or greater.
Furthermore, 7,399 intrauterine insemination cycles with husband''s semen and 1,302 with donor''s semen were registered. The majority involved women aged = 34. The clinical pregnancy rate was influenced by woman''s age, and the ovulation-induction protocol. Of the 1,134 babies born, 9% were twins and 1% = triple.
Finally, the previously-described regional tendencies became more pronounced during 2008: an increase in the IVF/ICSI transfer in women aged = 35; fertilization by means of ICSI; slight decrease in the mean number of transferred embryos; and improvement in live birth delivery rate per embryo transfer.